What to Know About Jim O’Neill, the New Acting C.D.C. Director

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The selection of Jim O’Neill, a former Silicon Valley executive, drew objections from Democrats, who noted his lack of medical or scientific training.

Robert F. Kennedy Jr., holding papers in his hands, looks to Jim O’Neill, who is raising his right hand while his left rests on a Bible.
Health Secretary Robert F. Kennedy Jr., right, swearing in Jim O’Neill as his deputy in June.Credit...Amy Rossetti/Department of Health and Human Services, via Associated Press

Emily Anthes

Aug. 29, 2025Updated 7:01 p.m. ET

On Thursday, the Trump administration selected Jim O’Neill, a former biotechnology executive and the deputy to Health Secretary Robert F. Kennedy Jr., to serve as the acting director of the Centers for Disease Control and Prevention.

The pick leaves the nation’s premier public health agency under the leadership of an official without medical or scientific training, and seems likely to tighten political control of the agency, critics in Congress said.

The decision follows a tumultuous few days at the agency in which its new director, Susan Monarez, was fired and several other top officials resigned. The departures were driven by deep disagreements over vaccine policy.

Mr. Kennedy, a longtime vaccine critic, is seeking to transform the nation’s vaccine policy; under his leadership, officials have already limited eligibility for Covid-19 vaccines.

In an email sent to C.D.C. staff on Thursday night, Mr. Kennedy said that he was “committed to working with you to restore trust, transparency and credibility” to the agency. Tapping Mr. O’Neill as acting director would “help advance this mission,” he added.

Mr. O’Neill was confirmed as the deputy secretary of health and human services in June. It was a return to the federal government for Mr. O’Neill, who also worked for the department from 2002 to 2008, under President George W. Bush.


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