What’s at Stake in the Iran-U.S. Nuclear Talks

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Plans for a third round of talks in three weeks have raised hopes for an Iran nuclear accord, which could avert a new Mideast conflict. President Trump said he believed a deal was within reach.

Pedestrians crossing a street under a large mural depicting Iran’s supreme leader, Ayatollah Ali Khamenei.
In Tehran this month. A new nuclear deal could transform Iran’s economic and political landscape by easing Western sanctions.Credit...Arash Khamooshi for The New York Times

Vivian NereimFarnaz Fassihi

April 26, 2025, 12:01 a.m. ET

A third round of talks between Iran and the United States over Tehran’s nuclear activities was planned for Saturday, raising hopes for a new accord that could avert another conflict in the Middle East.

“I think we’re going to make a deal with Iran. Nobody else could do that,” President Trump said in an interview with Time magazine published on Friday. Mr. Trump abandoned a previous nuclear deal with Iran in 2018 during his first term, saying it was a flawed agreement.

The talks have the potential to reshape regional and global security by reducing the chance of a U.S.-backed Israeli attack on Iranian nuclear facilities and preventing Iran from producing a nuclear weapon. A deal could also transform Iran’s economic and political landscape by easing American sanctions and opening the country up to foreign investors.

Steve Witkoff, Mr. Trump’s Middle East envoy; Abbas Araghchi, the Iranian foreign minister; and teams of technical experts from both sides will meet in the Gulf sultanate of Oman, which is mediating the talks.

This round will include the nuts-and-bolts “expert talks,” which bring together nuclear and financial teams from both sides to hash out technical details. These could include issues such as the monitoring of Iran’s nuclear facilities, its uranium enrichment levels and what will happen to its stockpiles of highly enriched uranium, along with easing sanctions.


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